There seems to be problems loop mounting ISO files with grub 2.04, how to downgrade to grub 2.02?
Grub 2.02 works for loop mounting ISO files on a Bootable pendrive.
I think the main problem comes when booting in UEFI mode.
Reference: Grub command loopback loop… does not work on Ubuntu 19.10 Grub command `loopback loop...` does not work on Ubuntu 19.10
Further Reference: LaunchPad https://bugs.launchpad.net/ubuntu/+source/grub2/+bug/1851311