By "run it from the start" I guess you mean the Unity launcher, the dash.
The best way is to create a .desktop launcher, first open a text editor, for example
gedit
Now copy this in to the file
[Desktop Entry]
Name=slic3r.desktop
Exec=./slic3r.pl
Icon=/path/to/your/icon
Type=Application
Terminal=false
Now save this as slic3r.desktop in your home directory and open a terminal and make it executable with
chmod +x ~/slic3r.desktop
Now double clicking this icon will run your program, to get it to appear in the dash like a normal application, move it to .local/share/applications
mv ~/slic3r.desktop ~/.local/share/applications
You can now search for slic3r in the dash, to add an icon change /path/to/your/icon for the path of the icon you would like.
Applications you build your self (or script programs) don't get an entry of there own in the dash, you can apply this to any program to create a launcher for it.