Alt+Space seems to be a Windows default shortcut, and I wish to disable it because it interferes with the controls of a game I play. I did some research and came upon PowerToys, it seemed very useful and I tried remapping Alt+Space to Disable, and changed the PowerToys Run shortcut to Ctrl+Space.
However Alt+Space is still bringing up that little window at the top left corner of app windows. Searched around and nobody else seems to encounter this issue.