(This may be better answered on serverfault, but it's not technically about a server, so suggestions welcome...)
We just moved offices at work. We're in Cambridge, MA, and have a Comcast business-class cable modem. Once every few days, for most of the day, we have trouble reaching some, but not all, web sites - for example, Slashdot. As it happens, I live three miles from the office, and I also have a Comcast business-class cable modem at home. From work, I can ssh into my server at home, and though I go through some of the same routers - and all of the same general POPs - I don't have these problems from home.
15 years ago, I knew how to troubleshoot this and call NOCs and figure it out. Nowadays, with load balancers and virtual IPs, I'm stumped. I tried contacting Savvis with the traceroutes below, and they said "It's not us". I sent them to Slashdot, and of course no response - but it's not just a Savvis problem and not just a Slashdot problem anyway.
We have also occasionally seen 10-30% packet loss when pinging Google's 8.8.8.8; I don't know if the problem occurs at the same time, and I don't have any failed traceroutes for that at the moment, but a successful traceroute leaves 111eighthave.ny.ibone.comcast.net and goes straight to Google without hitting Savvis.
Failing traceroute from the office:
~% traceroute slashdot.org
traceroute to slashdot.org (216.34.181.45), 64 hops max, 52 byte packets
1 * * *
2 te-7-1-ur01.cambridge.ma.boston.comcast.net (68.87.36.241) 10.628 ms 7.029 ms 14.147 ms
3 be-51-ar01.needham.ma.boston.comcast.net (68.85.162.157) 10.648 ms 13.714 ms 13.754 ms
4 pos-2-1-0-0-cr01.newyork.ny.ibone.comcast.net (68.86.95.29) 20.171 ms 18.774 ms 17.866 ms
5 pos-1-6-0-0-pe01.111eighthave.ny.ibone.comcast.net (68.86.87.110) 20.177 ms 18.549 ms 18.130 ms
6 er2-tengig3-3.newyork.savvis.net (208.173.138.13) 20.854 ms 19.490 ms 16.720 ms
7 cr1-tengig-0-8-3-0.newyork.savvis.net (204.70.198.13) 15.856 ms 20.863 ms 16.717 ms
8 cr2-tengig-0-0-2-0.chicago.savvis.net (204.70.196.242) 59.632 ms 47.147 ms 52.665 ms
9 hr2-tengigabitethernet-12-1.elkgrovech3.savvis.net (204.70.195.122) 40.771 ms 55.918 ms 39.418 ms
10 das4-v3044.ch3.savvis.net (64.37.207.206) 45.907 ms 45.159 ms 46.643 ms
11 64.27.160.198 (64.27.160.198) 42.509 ms 39.425 ms 67.412 ms
12 * * *
13 * * *
14 * * *
15 * * *
Successful traceroute from home:
~% traceroute slashdot.org
traceroute to slashdot.org (216.34.181.45), 64 hops max, 52 byte packets
1 73.164.80.1 (73.164.80.1) 10.194 ms 13.718 ms 9.876 ms
2 te-7-4-ur01.cambridge.ma.boston.comcast.net (68.85.160.17) 9.680 ms 6.937 ms 9.150 ms
3 be-51-ar01.needham.ma.boston.comcast.net (68.85.162.157) 8.392 ms 7.986 ms 8.621 ms
4 pos-2-2-0-0-cr01.newyork.ny.ibone.comcast.net (68.86.93.185) 16.350 ms 18.983 ms 19.961 ms
5 pos-1-4-0-0-pe01.111eighthave.ny.ibone.comcast.net (68.86.86.194) 17.208 ms 16.946 ms 20.909 ms
6 er2-tengig3-3.newyork.savvis.net (208.173.138.13) 16.934 ms 18.493 ms 23.790 ms
7 cr2-tengig-0-15-4-0.newyork.savvis.net (204.70.198.17) 26.530 ms 16.009 ms 14.924 ms
8 cr2-pos-0-7-3-0.chicago.savvis.net (204.70.192.109) 40.031 ms 39.496 ms 39.807 ms
9 hr2-tengigabitethernet-12-1.elkgrovech3.savvis.net (204.70.195.122) 41.065 ms 45.294 ms 41.091 ms
10 das3-v3039.ch3.savvis.net (64.37.207.186) 47.867 ms 40.606 ms 40.157 ms
11 64.27.160.194 (64.27.160.194) 50.774 ms 56.097 ms 51.147 ms
12 slashdot.org (216.34.181.45) 39.788 ms 41.741 ms 39.871 ms